Protein and cell engineering services

Deep mutational scanning, affinity maturation, enzyme optimization, stability engineering

Optimize function, stability, and expression through comprehensive variant characterization. Pooled screening of thousands of variants scored for multiple fitness parameters in a single experiment using yeast and mammalian display platforms.

CRISPR gene editing, stable cell lines, viral vector construction

Stable and reporter cell line development with landing pad technology, CRISPR gene editing, large-scale vector construction, and lentiviral vector production for your therapeutic or research programs.

Mutagenesis libraries, iterative selection, functional screening

Evolve your protein for improved activity, stability, or specificity through iterative rounds of mutagenesis and selection. Random and focused library approaches screened by display or functional assay, with NGS-quantified enrichment at each round.

RFdiffusion, BindCraft, Boltzgen — de novo binder discovery

Generate novel protein binders computationally using structure-guided diffusion models, then validate experimentally through our display platforms. Nanobodies, miniproteins, and custom scaffold binders for any target with a known structure.

Comprehensive fitness landscapes, variant scoring

Map the functional impact of every possible single amino acid substitution across your protein. Quantitative fitness landscapes for binding, expression, stability, and function — providing mechanistic insight into drug target biology and guiding rational engineering decisions.

Structure prediction, conformational sampling, sequence design

Leverage AlphaFold2, ColabFold, and Boltzgen for structure prediction and conformational ensemble generation. Improve activity and stability while screening fewer variants — computational pre-filtering reduces experimental burden. All tools we deploy use permissive MIT or Apache 2.0 licenses.