Ranomics
Cell culture and flow cytometry laboratory for cell engineering
Service

Cell engineering services

Cell engineering CRO services including CRISPR/Cas9 gene editing, stable and reporter cell line development with landing pad technology, large-scale vector construction, and lentiviral vector production

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CRISPRLanding PadLentivirusVector Construction

Create the exact cellular tools your research requires. Our cell engineering services provide robust, reliable, and highly customized solutions for everything from basic research to therapeutic development.

We thrive on complexity — successfully executing difficult edits and constructing large, multi-component genetic vehicles that other providers cannot. From CRISPR knockouts to landing pad cell lines, our team delivers.

Our cell engineering toolbox

Four core cell engineering and gene editing services

01

CRISPR/Cas9 gene editing

From simple knockouts to complex knock-ins and multiplex edits. End-to-end CRISPR services including guide RNA design, delivery optimization, and rigorous clonal validation. We precisely manipulate mammalian, yeast, and microbial genomes.

  • Single and multiplex gene knockouts
  • Targeted knock-in of transgenes and reporters
  • Point mutations and small insertions/deletions
  • Guide RNA design and off-target analysis
  • Clonal isolation and validation by sequencing
02

Stable and reporter cell line development

Generate high-performance, stable cell lines for cell-based assays and functional screening. Our landing pad technology enables seamless, site-specific integration of transgenes, ensuring consistent expression across clones and simplifying iterative cell line engineering.

  • Landing pad integration for seamless transgene insertion
  • CHO, HEK293, Jurkat, and custom host cells
  • Single-cell cloning and expansion
  • Expression stability testing over 30+ passages
  • Reporter cell lines for functional assays
  • Antibiotic selection and FACS-based enrichment
03

Large-scale vector construction

Our key differentiator: the ability to build and deliver complex, multi-operon knock-in vehicles. Express entire pathways or intricate synthetic circuits in a single construct. Multi-gene cassettes, pathway engineering, and synthetic biology.

  • Multi-gene expression cassettes (10+ genes)
  • Pathway reconstruction and optimization
  • Modular cloning and Golden Gate assembly
  • Codon optimization for target host
  • Sequence-verified with full QC documentation
04

Lentiviral vector production

Lentiviral vector production for efficient gene delivery to a wide range of cell types, including primary and non-dividing cells. Research-grade and preclinical-grade production with full titration and QC.

  • Lentivirus production and titration
  • Transduction optimization
  • Primary cell and non-dividing cell delivery
  • Research-grade and preclinical-grade production

Begin your cell engineering project

Don't let technical limitations define your scientific possibilities. Let's discuss how our advanced cell engineering capabilities can bring your most ambitious projects to life.

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