AI protein design tools, end to end
Free epitope and developability triage, GPU-backed de novo binder design, and structure prediction, all on a single USD wallet alongside the Ranomics yeast display CRO.
Free to start with a $5 wallet balance on signup. Fund a wallet after that and pay only for the compute delivered. Used by academic labs, seed biotechs, and industrial R&D groups to scope campaigns before committing compute or wet lab budget.
Free to run, no wallet needed
Epitope Scout
Ranks surface epitope patches on a target protein for binder design campaigns, scored on hydrophobic exposure, structural order, rigidity, surface accessibility, and hot spot density.
Read more → Free foreverBinder Developability Scout
Aggregated liability score for antibody, nanobody, and de novo binder sequences covering hydrophobic patches, charge distribution, glycosylation motifs, and aggregation-prone regions.
Read more →De novo binder design + structure prediction
Run on dedicated GPUs. No shared batch queues, no place in line. Funded from your wallet, with no per design charge. Per job guardrails keep a bad input from running away with your balance.
BindCraft
De novo binder design via AlphaFold2 multimer with hotspot-focused backpropagation. Best when you have a target PDB plus known hotspots.
RFdiffusion
Diffusion-based de novo backbone generator paired with ProteinMPNN sequence design and AF2 multimer scoring. General-purpose binder design with calibrated confidence.
RFantibody
Antibody-specific RFdiffusion fine-tune. Generates VHH (single-domain / nanobody) and scFv scaffolds against a target.
BoltzGen
All-atom diffusion de novo binder design (MIT BoltzGen), choosing backbone and sequence together, with a built-in refolding self-consistency check.
PXDesign
ByteDance's open binder designer, built on the AlphaFold3-class Protenix model and scored with AF2 Initial Guess. The same tool we run on our wet lab campaigns.
ProteinMPNN
Sequence design for an existing backbone. Pair with any of the binder-design tools above to redesign sequences on the generated structures.
AlphaFold2
Gold-standard structure prediction with full MSA + templates and calibrated pLDDT / PAE. Monomer or multimer.
ColabFold
Fast no-MSA AF2 fold. 1 to 2 minutes per run when you need throughput and can tolerate slightly lower accuracy than full-MSA AF2.
Self serve to wet lab CRO, one ladder
Start free, scale into self serve when you are running real campaigns, hand off to the wet lab when a design is worth validating in cells.
Free to start
$5 in your wallet on signup. Epitope Scout and Developability Scout stay free. The wallet is prepaid, so you can only ever spend what you have funded.
Sign up free →Wallet, no subscription
Top up in any amount from $20 and pay only for the compute delivered. Per job guardrails keep a bad input from running away with your balance. No credits, no tiers, no subscriptions.
See pricing →Auto reload, optional
Save a card to auto reload when balance runs low. Limited to one charge per 24 hours plus a monthly cap you set.
See safety controls →Binder Pilot
Single round, smaller design pool. Wet lab validation included. Smallest CRO entry point.
See the Pilot →AI Binder Sprint
6 to 8 weeks, multi algorithm, 100 percent binder guarantee. Flagship offering.
See the Sprint →Custom campaign
Open scope, multi target, multi round, pharma grade. For programs at scale.
See services →Need the full campaign run end to end?
Self serve tools give you the design layer. Binder Pilot adds wet lab validation, yeast display sorting, and a technical report. It is the smallest CRO entry point we offer.
See the Binder Pilot →