AI protein design tools, end to end
Free epitope and developability triage, GPU-backed de novo binder design, structure prediction, and yeast display library planning, all on a single USD wallet alongside the Ranomics yeast display CRO.
Free to start with $5 of compute credit on signup. Pay as you go after that. Used by academic labs, seed biotechs, and industrial R&D groups to scope campaigns before committing compute or wet lab budget.
Free trial credit covers most usage
Epitope Scout
Ranks surface epitope patches on a target protein for binder design campaigns, scored by hydrophilicity, conservation, and pocket geometry.
Read more → Free foreverBinder Developability Scout
Aggregated liability score for antibody, nanobody, and de novo binder sequences covering hydrophobic patches, charge distribution, glycosylation motifs, and aggregation-prone regions.
Read more → Free foreverYeast Display Library Planner
Designs feasibility-ranked NNK or NNS mutation libraries against a parent scaffold, with diversity math, expression-readiness flags, and primer plans.
Read more →De novo binder design + structure prediction
Run on dedicated GPUs. No shared batch queues, no place in line. Metered against your wallet, with per job hard caps so a bad input can never run away with your balance.
BindCraft
De novo binder design via AlphaFold2 multimer with hotspot-focused backpropagation. Best when you have a target PDB plus known hotspots.
RFdiffusion
Diffusion-based de novo backbone generator paired with ProteinMPNN sequence design and AF2 multimer scoring. General-purpose binder design with calibrated confidence.
RFantibody
Antibody-specific RFdiffusion fine-tune. Generates VHH (single-domain / nanobody) and scFv scaffolds against a target.
BoltzGen
Boltz-2 binder design with native support for glycans, post-translational modifications, and non-canonical residues. Refolds candidates end to end.
PXDesign
Ranomics in-house pipeline. RFdiffusion-style backbone generation with JAX AF2 Initial Guess scoring. Same pipeline that drives our wet lab campaigns.
ProteinMPNN
Sequence design for an existing backbone. Pair with any of the binder-design tools above to redesign sequences on the generated structures.
AlphaFold2
Gold-standard structure prediction with full MSA + templates and calibrated pLDDT / PAE. Monomer or multimer.
ColabFold
Fast no-MSA AF2 fold. 1 to 2 minutes per run when you need throughput and can tolerate slightly lower accuracy than full-MSA AF2.
Self serve to wet lab CRO, one ladder
Start free, scale into self serve when you are running real campaigns, hand off to the wet lab when a design is worth validating in cells.
Free to start
$5 of compute credit on signup. Unlimited smoke runs. Most evaluation runs cost cents.
Sign up free →Wallet, pay as you go
Top up in any amount from $20. Per job pricing, per second compute. No subscription, no seats, no tiers.
See pricing →Auto reload, optional
Save a card to auto reload when balance runs low. Limited to one charge per 24 hours plus a monthly cap you set.
See safety controls →Binder Pilot
Single round, smaller design pool. Wet lab validation included. Smallest CRO entry point.
See the Pilot →AI Binder Sprint
6 to 8 weeks, multi algorithm, 100 percent binder guarantee. Flagship offering.
See the Sprint →Custom campaign
Open scope, multi target, multi round, pharma grade. For programs at scale.
See services →Need the full campaign run end to end?
Self serve tools give you the design layer. Binder Pilot adds wet lab validation, yeast display sorting, and a technical report. It is the smallest CRO entry point we offer.
See the Binder Pilot →